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Investor directory

Venture capital firms in Boston: a 2026 guide.

This directory lists 18 venture capital firms based in Boston and Cambridge, from seed funds such as Founder Collective and Underscore VC to multi-stage firms such as General Catalyst and biotech company creators such as Flagship Pioneering.

The Boston and Cambridge directory

18 firms in this view

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Accelerators, studios and programs (1)

Accelerators, startup studios and other structured programs that invest at the start, often alongside mentoring or a cohort.

Pre-seed and seed (6)

Firms that say they write first checks. Some also lead or join Series A rounds.

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Early stage (5)

Firms that describe themselves as early-stage investors, typically around Series A and B.

  • .406 Ventures

    A Boston early-stage investor focused on healthcare, data and AI, and cybersecurity.

    Stated focus
    Healthcare, data and AI, cybersecurity
    Stage
    Early (Series A/B)
    Headquarters or office
    Boston, MA
    Last verified
    September 2026
    Visit the firm's website (.406 Ventures, opens in a new tab)Suggest a correction for .406 Ventures
    Read the profile: .406 Ventures
    Stage
    Early stage
    Focus
    Healthcare, data and AI, cybersecurity
    Location
    Boston, MA
    Founded
    Not stated in the checked sources
    Categories
    Early (Series A/B) · AI · Healthcare / bio
    Sources checked (September 2026)
    406ventures.com

  • Atlas Venture

    Based in Cambridge, it creates and backs early-stage biotechnology companies.

    Stated focus
    Biotechnology
    Stage
    Early (Series A/B)
    Headquarters or office
    Cambridge, MA
    Last verified
    September 2026
    Visit the firm's website (Atlas Venture, opens in a new tab)Suggest a correction for Atlas Venture
    Read the profile: Atlas Venture
    Stage
    Company creation and early stage
    Focus
    Biotechnology
    Location
    Cambridge, MA
    Founded
    Not stated in the checked sources
    Categories
    Early (Series A/B) · Healthcare / bio
    Sources checked (September 2026)
    atlasventure.com

  • Battery Ventures

    Founded in 1983, it makes venture and private equity investments in application and infrastructure software, consumer and industrial tech, with offices in Boston, the Bay Area and London.

    Stated focus
    Application software, infrastructure software, consumer, industrial tech
    Stage
    Early (Series A/B)
    Headquarters or office
    Boston, MA
    Last verified
    September 2026
    Visit the firm's website (Battery Ventures, opens in a new tab)Suggest a correction for Battery Ventures
    Read the profile: Battery Ventures
    Stage
    Venture and private equity
    Focus
    Application software, infrastructure software, consumer, industrial tech
    Location
    Boston, MA (also Menlo Park, San Francisco, Israel, London)
    Founded
    Founded in 1983
    Categories
    Early (Series A/B) · Enterprise / B2B software · Consumer
    Sources checked (September 2026)
    battery.comen.wikipedia.org/wiki/Battery_Ventures

  • Glasswing Ventures

    An early-stage investor in AI-native and frontier technology for enterprise B2B and cybersecurity.

    Stated focus
    AI-native and frontier tech for enterprise B2B and cybersecurity
    Stage
    Early (Series A/B)
    Headquarters or office
    Boston, MA
    Last verified
    September 2026
    Visit the firm's website (Glasswing Ventures, opens in a new tab)Suggest a correction for Glasswing Ventures
    Read the profile: Glasswing Ventures
    Stage
    Early stage
    Focus
    AI-native and frontier tech for enterprise B2B and cybersecurity
    Location
    Boston, MA
    Founded
    Not stated in the checked sources
    Categories
    Early (Series A/B) · AI · Enterprise / B2B software · Deep tech / hardware
    Sources checked (September 2026)
    glasswing.vc

  • Highland Capital Partners

    An early-stage technology investor in Cambridge and Boston, founded by Paul Maeder and Bob Higgins.

    Stated focus
    Technology
    Stage
    Early (Series A/B)
    Headquarters or office
    Cambridge/Boston, MA
    Last verified
    September 2026
    Visit the firm's website (Highland Capital Partners, opens in a new tab)Suggest a correction for Highland Capital Partners
    Read the profile: Highland Capital Partners
    Stage
    Early stage
    Focus
    Technology
    Location
    Cambridge/Boston, MA
    Founded
    by Paul Maeder; Bob Higgins
    Categories
    Early (Series A/B) · Generalist
    Sources checked (September 2026)
    hcp.comen.wikipedia.org/wiki/Highland_Capital_Partners

Multi-stage and growth (4)

Firms that invest across stages or in later rounds, from early checks through growth.

Other investment models (2)

Company builders, crypto funds, public and private investors and other models that do not fit a stage label.

How to use this directory

Boston's firms lean toward life sciences more than those of the other large hubs in our research: 8 of the 18 firms here list healthcare or biotech among their interests, against about a third in the Bay Area and one in New York. Some of them create companies themselves.

  • Filter by stage first. 8 firms carry a pre-seed or seed label, based on their own descriptions.
  • Know the model. Company creators such as Third Rock Ventures build companies themselves, and The Engine is a nonprofit incubator and accelerator. They sit in their own groups.
  • Headquarters is not the only office. The grid shows each firm's headquarters; the profile lists every location we verified, including New York, the Bay Area and London.
  • Read how the firm wants to hear from founders on its own site before you reach out.

Why Boston matters for venture capital

Massachusetts is the third-largest state for venture investment, after California and New York. In 2025, companies based there drew $16.5 billion of the $320.0 billion invested in US venture-backed companies, or 5.14%, across 825 companies, according to the PitchBook data in the NVCA 2026 Yearbook.

This directory covers the 18 Boston and Cambridge firms with enough public evidence for an accurate profile. Several also run offices in New York or San Francisco; a New York-headquartered firm with a Boston office appears in our New York directory instead.

How we built this directory

We group firms by their stated investment focus and the research classifications in this directory. A category match is a reason to investigate, not evidence that a firm will invest. Current terms and contact instructions belong on the firm's own website.

Each record lists the pages we checked for it and when. Inclusion means a firm has enough public information to profile accurately, not that it is investing now.

Corrections, and what is not here

Firms change. If a detail is out of date, use Suggest a correction on the firm's row and include your source. We do not list fund sizes, email addresses or phone numbers; the firm's own site is the source for current terms and how to reach it.

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Frequently asked questions

How many venture capital firms are in Boston?

There is no official count by city. This directory profiles 18 Boston and Cambridge firms with enough public evidence to describe accurately. In 2025, Massachusetts companies drew 5.14% of US venture investment, per the NVCA 2026 Yearbook.

Which Boston VC firms invest at seed?

In this directory, 8 Boston and Cambridge firms carry a pre-seed or seed label, based on their own descriptions. Filter by investment stage to see them, then confirm on each firm's site that it still invests at that stage.

Which Boston venture capital firms focus on biotech and healthcare?

8 firms in this directory list healthcare or biotech among their interests, including Atlas Venture, Flagship Pioneering, Third Rock Ventures and Polaris Partners. Filter by the Healthcare / bio sector to see them all.

Is this a list of investors who will fund my startup?

No. Inclusion means a firm has enough public information to profile, not that it is investing now or would invest in you. A category match is a reason to research a firm further, not a prediction.

Sources

Checked September 13, 2026. Each firm's profile lists the pages we checked for it. This is information, not investment or fundraising advice.

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