Venture capital firms in Boston: a 2026 guide.
This directory lists 18 venture capital firms based in Boston and Cambridge, from seed funds such as Founder Collective and Underscore VC to multi-stage firms such as General Catalyst and biotech company creators such as Flagship Pioneering.
The Boston and Cambridge directory
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Accelerators, studios and programs (1)
Accelerators, startup studios and other structured programs that invest at the start, often alongside mentoring or a cohort.
The Engine
A nonprofit incubator and accelerator founded by MIT in 2016 for what it calls Tough Tech, from biotech to climate tech.
- Stated focus
- Tough Tech: biotech, climate tech and beyond
- Stage
- Accelerator / program
- Headquarters or office
- Cambridge, MA
- Last verified
- September 2026
Read the profile: The Engine
- Stage, in the firm's words
- Incubator and accelerator (nonprofit)
- Focus, in the firm's words
- Tough Tech: biotech, climate tech and beyond
- Location, as verified
- Cambridge, MA
- Founded
- Founded in 2016 by MIT
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Accelerator / program · Healthcare / bio · Climate / energy · Deep tech / hardware
- Sources checked (September 2026)
- engine.xyzen.wikipedia.org/wiki/The_Engine_(organization)
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Pre-seed and seed (6)
Firms that say they write first checks. Some also lead or join Series A rounds.
Founder Collective
A seed fund founded in 2009 by David Frankel and Eric Paley, investing in early-stage technology from Cambridge and New York.
- Stated focus
- Early-stage technology
- Stage
- Seed
- Headquarters or office
- Cambridge, MA and New York, NY
- Last verified
- September 2026
Visit the firm's website (Founder Collective, opens in a new tab)Suggest a correction for Founder CollectiveRead the profile: Founder Collective
- Stage, in the firm's words
- Seed
- Focus, in the firm's words
- Early-stage technology
- Location, as verified
- Cambridge, MA and New York, NY
- Founded
- Founded in 2009 by David Frankel; Eric Paley
- Companies named by the firm or in press
- Airtable, Coupang, Uber, Shield AI
- Our research labels
- Seed · AI
- Sources checked (September 2026)
- foundercollective.comen.wikipedia.org/wiki/Founder_Collective
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Hyperplane
A seed investor in AI, robotics and enterprise infrastructure.
- Stated focus
- AI, robotics, enterprise infrastructure
- Stage
- Seed
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Read the profile: Hyperplane
- Stage, in the firm's words
- Seed
- Focus, in the firm's words
- AI, robotics, enterprise infrastructure
- Location, as verified
- Boston, MA (137 Newbury St, per public profiles)
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Seed · AI · Enterprise / B2B software · Deep tech / hardware
- Sources checked (September 2026)
- hyperplane.vccrunchbase.com/organization/hyperplane-venture-capital
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Matrix
Founded in 1977 by Paul Ferri, it invests from the idea stage through Series A in software, AI, communications, semiconductors and internet companies, from Boston and the Bay Area.
- Stated focus
- Software, AI, communications, semiconductors, internet
- Stage
- Pre-seedEarly (Series A/B)
- Headquarters or office
- Bay Area and Boston
- Last verified
- September 2026
Read the profile: Matrix
- Stage, in the firm's words
- Idea through Series A
- Focus, in the firm's words
- Software, AI, communications, semiconductors, internet
- Location, as verified
- Bay Area and Boston (Wikipedia lists Palo Alto)
- Founded
- Founded in 1977 by Paul Ferri
- Companies named by the firm or in press
- Apple, FedEx, Oculus, Canva
- Our research labels
- Pre-seed · Early (Series A/B) · AI · Enterprise / B2B software · Deep tech / hardware
- Sources checked (September 2026)
- matrix.vcen.wikipedia.org/wiki/Matrix_Partners
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
NextView Ventures
A seed-stage technology investor with offices in New York, San Francisco and Boston.
- Stated focus
- Technology
- Stage
- Seed
- Headquarters or office
- New York, San Francisco and Boston
- Last verified
- September 2026
Visit the firm's website (NextView Ventures, opens in a new tab)Suggest a correction for NextView VenturesRead the profile: NextView Ventures
- Stage, in the firm's words
- Seed
- Focus, in the firm's words
- Technology
- Location, as verified
- Offices in New York, San Francisco and Boston
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Seed · Generalist
- Sources checked (September 2026)
- nextview.vc
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Pillar VC
A pre-seed and seed investor in technical breakthroughs, science and university startups.
- Stated focus
- Technical breakthroughs, science and university startups
- Stage
- Pre-seedSeed
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Read the profile: Pillar VC
- Stage, in the firm's words
- Pre-seed and seed
- Focus, in the firm's words
- Technical breakthroughs, science and university startups
- Location, as verified
- Boston, MA
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Pre-seed · Seed · Generalist
- Sources checked (September 2026)
- pillar.vc
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Underscore VC
A pre-seed and seed investor in B2B software.
- Stated focus
- B2B software
- Stage
- Pre-seedSeed
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Read the profile: Underscore VC
- Stage, in the firm's words
- Pre-seed and seed
- Focus, in the firm's words
- B2B software
- Location, as verified
- Boston, MA
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Pre-seed · Seed · Enterprise / B2B software
- Sources checked (September 2026)
- underscore.vc
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
//Free investor research file
Keep your Boston investor research together.
Save the firms, stated focus, official websites and details that still need checking.
Early stage (5)
Firms that describe themselves as early-stage investors, typically around Series A and B.
.406 Ventures
A Boston early-stage investor focused on healthcare, data and AI, and cybersecurity.
- Stated focus
- Healthcare, data and AI, cybersecurity
- Stage
- Early (Series A/B)
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Read the profile: .406 Ventures
- Stage, in the firm's words
- Early stage
- Focus, in the firm's words
- Healthcare, data and AI, cybersecurity
- Location, as verified
- Boston, MA
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · AI · Healthcare / bio
- Sources checked (September 2026)
- 406ventures.com
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Atlas Venture
Based in Cambridge, it creates and backs early-stage biotechnology companies.
- Stated focus
- Biotechnology
- Stage
- Early (Series A/B)
- Headquarters or office
- Cambridge, MA
- Last verified
- September 2026
Read the profile: Atlas Venture
- Stage, in the firm's words
- Company creation and early stage
- Focus, in the firm's words
- Biotechnology
- Location, as verified
- Cambridge, MA
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · Healthcare / bio
- Sources checked (September 2026)
- atlasventure.com
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Battery Ventures
Founded in 1983, it makes venture and private equity investments in application and infrastructure software, consumer and industrial tech, with offices in Boston, the Bay Area and London.
- Stated focus
- Application software, infrastructure software, consumer, industrial tech
- Stage
- Early (Series A/B)
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Visit the firm's website (Battery Ventures, opens in a new tab)Suggest a correction for Battery VenturesRead the profile: Battery Ventures
- Stage, in the firm's words
- Venture and private equity
- Focus, in the firm's words
- Application software, infrastructure software, consumer, industrial tech
- Location, as verified
- Boston, MA (also Menlo Park, San Francisco, Israel, London)
- Founded
- Founded in 1983
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · Enterprise / B2B software · Consumer
- Sources checked (September 2026)
- battery.comen.wikipedia.org/wiki/Battery_Ventures
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Glasswing Ventures
An early-stage investor in AI-native and frontier technology for enterprise B2B and cybersecurity.
- Stated focus
- AI-native and frontier tech for enterprise B2B and cybersecurity
- Stage
- Early (Series A/B)
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Visit the firm's website (Glasswing Ventures, opens in a new tab)Suggest a correction for Glasswing VenturesRead the profile: Glasswing Ventures
- Stage, in the firm's words
- Early stage
- Focus, in the firm's words
- AI-native and frontier tech for enterprise B2B and cybersecurity
- Location, as verified
- Boston, MA
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · AI · Enterprise / B2B software · Deep tech / hardware
- Sources checked (September 2026)
- glasswing.vc
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Highland Capital Partners
An early-stage technology investor in Cambridge and Boston, founded by Paul Maeder and Bob Higgins.
- Stated focus
- Technology
- Stage
- Early (Series A/B)
- Headquarters or office
- Cambridge/Boston, MA
- Last verified
- September 2026
Visit the firm's website (Highland Capital Partners, opens in a new tab)Suggest a correction for Highland Capital PartnersRead the profile: Highland Capital Partners
- Stage, in the firm's words
- Early stage
- Focus, in the firm's words
- Technology
- Location, as verified
- Cambridge/Boston, MA
- Founded
- by Paul Maeder; Bob Higgins
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · Generalist
- Sources checked (September 2026)
- hcp.comen.wikipedia.org/wiki/Highland_Capital_Partners
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Multi-stage and growth (4)
Firms that invest across stages or in later rounds, from early checks through growth.
Bain Capital Ventures
Invests from seed through growth in apps, infrastructure, commerce, fintech, healthcare, physical AI and security, from Boston, New York, San Francisco and Palo Alto; founded in 2001.
- Stated focus
- Apps, infrastructure, commerce, fintech, healthcare, physical AI, security
- Stage
- SeedGrowth
- Headquarters or office
- Boston, New York, San Francisco and Palo Alto
- Last verified
- September 2026
Visit the firm's website (Bain Capital Ventures, opens in a new tab)Suggest a correction for Bain Capital VenturesRead the profile: Bain Capital Ventures
- Stage, in the firm's words
- Seed through growth
- Focus, in the firm's words
- Apps, infrastructure, commerce, fintech, healthcare, physical AI, security
- Location, as verified
- Offices in Boston, New York, San Francisco and Palo Alto
- Founded
- Founded in 2001
- Companies named by the firm or in press
- DocuSign, Attentive, Flywire
- Our research labels
- Seed · Growth · AI · Enterprise / B2B software · Fintech · Healthcare / bio · Consumer · Deep tech / hardware
- Sources checked (September 2026)
- baincapitalventures.comen.wikipedia.org/wiki/Bain_Capital_Ventures
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
General Catalyst
Founded in 2000 by Joel Cutler and David Fialkow, it invests at seed, venture and growth stages in applied AI, healthcare, resilience and more.
- Stated focus
- Applied AI, healthcare, resilience and more
- Stage
- SeedGrowth
- Headquarters or office
- Cambridge, MA
- Last verified
- September 2026
Visit the firm's website (General Catalyst, opens in a new tab)Suggest a correction for General CatalystRead the profile: General Catalyst
- Stage, in the firm's words
- Seed, venture and growth
- Focus, in the firm's words
- Applied AI, healthcare, resilience and more
- Location, as verified
- Cambridge, MA (also Bay Area offices)
- Founded
- Founded in 2000 by Joel Cutler; David Fialkow
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Seed · Growth · AI · Healthcare / bio
- Sources checked (September 2026)
- generalcatalyst.comen.wikipedia.org/wiki/General_Catalyst
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Polaris Partners
Founded in 1996, it invests in healthcare and biotechnology at early and growth stages.
- Stated focus
- Healthcare and biotechnology
- Stage
- Early (Series A/B)Growth
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Visit the firm's website (Polaris Partners, opens in a new tab)Suggest a correction for Polaris PartnersRead the profile: Polaris Partners
- Stage, in the firm's words
- Early and growth
- Focus, in the firm's words
- Healthcare and biotechnology
- Location, as verified
- Boston, MA (also New York and San Francisco)
- Founded
- Founded in 1996
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Early (Series A/B) · Growth · Healthcare / bio
- Sources checked (September 2026)
- polarispartners.comen.wikipedia.org/wiki/Polaris_Partners
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Spark Capital
A multi-stage generalist founded in 2005, investing in consumer internet, enterprise software, gaming and infrastructure from San Francisco, New York and Boston.
- Stated focus
- Generalist: consumer internet, enterprise software, gaming, infrastructure
- Stage
- Multi-stage
- Headquarters or office
- San Francisco, New York and Boston
- Last verified
- September 2026
Read the profile: Spark Capital
- Stage, in the firm's words
- Multi-stage
- Focus, in the firm's words
- Generalist: consumer internet, enterprise software, gaming, infrastructure
- Location, as verified
- San Francisco, New York and Boston
- Founded
- Founded in 2005
- Companies named by the firm or in press
- Our research labels
- Multi-stage · Enterprise / B2B software · Consumer
- Sources checked (September 2026)
- sparkcapital.comen.wikipedia.org/wiki/Spark_Capital
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Other investment models (2)
Company builders, crypto funds, public and private investors and other models that do not fit a stage label.
Flagship Pioneering
A Cambridge company creator, founded in 1999, that builds companies in biotechnology, life sciences, health and sustainability.
- Stated focus
- Biotechnology, life sciences, health, sustainability
- Stage
- Other investment models
- Headquarters or office
- Cambridge, MA
- Last verified
- September 2026
Visit the firm's website (Flagship Pioneering, opens in a new tab)Suggest a correction for Flagship PioneeringRead the profile: Flagship Pioneering
- Stage, in the firm's words
- Company creation
- Focus, in the firm's words
- Biotechnology, life sciences, health, sustainability
- Location, as verified
- Cambridge, MA
- Founded
- Founded in 1999
- Companies named by the firm or in press
- Moderna, Indigo Ag
- Our research labels
- Other investment models · Healthcare / bio · Climate / energy
- Sources checked (September 2026)
- flagshippioneering.comen.wikipedia.org/wiki/Flagship_Pioneering
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
Third Rock Ventures
A Boston company creator in healthcare, science and medicine, with an office in San Francisco.
- Stated focus
- Healthcare, science and medicine
- Stage
- Other investment models
- Headquarters or office
- Boston, MA
- Last verified
- September 2026
Visit the firm's website (Third Rock Ventures, opens in a new tab)Suggest a correction for Third Rock VenturesRead the profile: Third Rock Ventures
- Stage, in the firm's words
- Company creation
- Focus, in the firm's words
- Healthcare, science and medicine
- Location, as verified
- Boston, MA (also San Francisco)
- Founded
- Not stated in the checked sources
- Companies named by the firm or in press
- Not stated in the checked sources
- Our research labels
- Other investment models · Healthcare / bio
- Sources checked (September 2026)
- thirdrockventures.com
Check size, fund size and how to reach the firm are not listed here. The firm's own website is the source for current terms and contact instructions.
How to use this directory
Boston's firms lean toward life sciences more than those of the other large hubs in our research: 8 of the 18 firms here list healthcare or biotech among their interests, against about a third in the Bay Area and one in New York. Some of them create companies themselves.
- Filter by stage first. 8 firms carry a pre-seed or seed label, based on their own descriptions.
- Know the model. Company creators such as Third Rock Ventures build companies themselves, and The Engine is a nonprofit incubator and accelerator. They sit in their own groups.
- Headquarters is not the only office. The grid shows each firm's headquarters; the profile lists every location we verified, including New York, the Bay Area and London.
- Read how the firm wants to hear from founders on its own site before you reach out.
Why Boston matters for venture capital
Massachusetts is the third-largest state for venture investment, after California and New York. In 2025, companies based there drew $16.5 billion of the $320.0 billion invested in US venture-backed companies, or 5.14%, across 825 companies, according to the PitchBook data in the NVCA 2026 Yearbook.
This directory covers the 18 Boston and Cambridge firms with enough public evidence for an accurate profile. Several also run offices in New York or San Francisco; a New York-headquartered firm with a Boston office appears in our New York directory instead.
How we built this directory
We group firms by their stated investment focus and the research classifications in this directory. A category match is a reason to investigate, not evidence that a firm will invest. Current terms and contact instructions belong on the firm's own website.
Each record lists the pages we checked for it and when. Inclusion means a firm has enough public information to profile accurately, not that it is investing now.
Corrections, and what is not here
Firms change. If a detail is out of date, use Suggest a correction on the firm's row and include your source. We do not list check sizes, fund sizes or contact details; the firm's own site is the source for those.
Investor research and marketing are separate jobs, and this directory is only about the first. If marketing is on your list too, our page on marketing for technology companies explains how we work.
Frequently asked questions
How many venture capital firms are in Boston?
There is no official count by city. This directory profiles 18 Boston and Cambridge firms with enough public evidence to describe accurately. In 2025, Massachusetts companies drew 5.14% of US venture investment, per the NVCA 2026 Yearbook.
Which Boston VC firms invest at seed?
In this directory, 8 Boston and Cambridge firms carry a pre-seed or seed label, based on their own descriptions. Filter by investment stage to see them, then confirm on each firm's site that it still invests at that stage.
Which Boston venture capital firms focus on biotech and healthcare?
8 firms in this directory list healthcare or biotech among their interests, including Atlas Venture, Flagship Pioneering, Third Rock Ventures and Polaris Partners. Filter by the Healthcare / bio sector to see them all.
Is this a list of investors who will fund my startup?
No. Inclusion means a firm has enough public information to profile, not that it is investing now or would invest in you. A category match is a reason to research a firm further, not a prediction.
Sources
Checked September 13, 2026. Each firm's profile lists the pages we checked for it. This is information, not investment or fundraising advice.
- NVCA 2026 Yearbook, public data pack (page 13; data provided by PitchBook): 2025 venture investment and company counts by state
- NVCA 2026 Yearbook: the yearbook and its methodology
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